NVIDIA is currently investigating end user reports that after updating to NVIDIA Game Ready Driver 461.09 or newer, Google Chrome may display flicker on some PC configurations.
Workaround:
Users who are experiencing this issue may download the registry file "mpo_disable.reg" from the Attachments section below and proceed to double-click on the file to add it to your system registry. This registry file will disable multiplane overlay. After adding the registry file, reboot your PC to complete the changes. If the flicker persists, you may restore multiplane overlay by downloading the file "mpo_restore.reg" and then proceed to double-click on the file to add it to your registry.