When using a supported Quadro card and a supported display, no special configuration is required to enable 30-bit color. The driver by default switches to 30-bit scan out when connected to a 30-bit capable supported monitor. Information on supported cards, displays, and operating systems is available at the link below.
On Windows Vista and Windows 7, this mode automatically disables Windows Aero regardless of whether a 30-bit application is running. If Aero must be enabled (therefore reverting to 24-bit color rendering), the NVIDIA Control Panel has a "Deep Color for 3D Applications" setting that can be set to “disable." This setting is available under Manage 3D Settings using the Program Settings Tab and the Base Profile in the Gloabl Presets pull-down menu.